Chorionic gonadotropin is prescribed intramuscularly. The dose is individualized depending on the nature, severity of the disease and the age of the patient and ranges from 500 to 3000 IU per day.
For men, the drug is administered 2-3 times a week in courses of 4 weeks at intervals of 4-6 weeks. 3-6 courses are carried out within 6-12 months. Long-term continuous use of the drug is not recommended due to the risk of antibody formation and suppression of the pituitary gonadotropic function.
With anovulatory cycles with a high level of estrogen in women, which indicates the normal maturation of follicles, the drug is administered starting from the 10-12th day of the cycle, 3000 U 2-3 times with an interval of 2-3 days or 1500 U 6-7 times every day.
In case of interstitial pituitary insufficiency, treatment with chorionic gonadotropin is best carried out after preliminary treatment in the first phase of the cycle with follicle-stimulating hormone. In case of pituitary dwarfism with symptoms of sexual infantilism, the drug is administered at a dose of 500-1000 IU 1-2 times a week for 1-2 months by repeated courses.
Chorionic gonadotropin treatment of cryptorchidism in children is most effective under the age of 10 years. The dosage and duration of treatment are individual, depending on the location of the undescended testicle and the nature of cryptorchidism (unilateral or bilateral). The most common treatment regimen is as follows: for cryptorchidism in children under 10 years of age, 500-1000 units are administered, at the age of 10-14 years – 1500 units 2 times a week for 4-6 weeks by repeated courses.
For diagnostic purposes, the drug is administered to men at 1500-3000 IU per day for 5 days. With a positive test result, the daily urinary excretion of 17-ketosteroids and testosterone increases.